Cytrans® Granules is a synthetic bone graft material having a similar composition with inorganic component of human bone. Cytrans® Granules has an unique balance of bone formation and bone replacement which helps to keep the volume of regenerated bone for predictable outcome. Cytrans® Granules is free from animal derived materials so the patients do not need to be worried about disease transmission, such as BSE.
Source: Prof. Ishikawa, Kyushu University, Japan
Thanks to the excellent osteoconductivity of carbonated apatite, early bone formation could be expected around Cytrans® Granules.
[AB] Autologous bone
[C] Cytrans® Granules
[BV] Blood vessel
[NB] Newly formed bone
SEM image of Cytrans® Granules implanted to canine tooth socket.
Source: Prof. Matsuo, Kanagawa Dental University, Japan.
Resorption property of carbonate apatite will allow the gradual replacement with host bone. Cytrans® Granules will be replaced by keeping the function as a scaffold.
Resorption of Cytrans® Granules implanted to rabbit femoral defect.
Source: Prof. Matsuo, Kanagawa Dental University, Japan.
Unlike other calcium phosphate materials, Cytrans® Granules are fabricated without sintering by maintaining a rough surface similar to that of natural bone. This rough surface makes Cytrans® Granules hydrophilic, allowing them to be mixed with blood or saline for easy delivery.
Pre-op
After grafting
After 6 months
Courtesy of Dr. Akiyoshi Funato, Japan
Pre-op
After grafting
After 6 months
Courtesy of Dr. Yoshifumi Matsumoto, Japan
Defect configuration
After grafting
After 12 months
Courtesy of Dr. Noriko Tachikawa, Japan
S size
M size